Headache & Pain Relief Medicines

Don't suffer in silence. Treat minor pain, from headaches to joint pain, with a range of painkillers you can trust. Find tablets, creams and gels, from Nurofen, Voltarol and more. Our experienced team of in-house pharmacists work to source the very best pain relief medications and treatments available for our customers. Check out our pain relief products today!

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  • Nurofen Plus 200mg Nurofen Plus 200mg 32 Tablets

    Nurofen Plus tablets can be used for the short-term relief of rheumatic and muscular pain, backache, migraine, headache, neuralgia, period pain and dental pain. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    150 reviews In Stock
    £11.99
  • Emla 5% Cream (No Dressings) Emla 5% Cream (No Dressings) 30g

    Emla Cream - 30g Tube (No Dressings) is used to ease the pain of medical or cosmetic needle procedures, including injections and superficial skin procedures.

    79 reviews In Stock
    £19.79
  • Co-codamol 8/500mg Co-codamol 8/500mg 32 Tablets

    Co-codamol 8/500 tablets can be used for the short-term relief of acute, moderate pain associated with headache, migraine, neuralgia, toothache, dysmenorrhoea and rheumatic pain. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    235 reviews In Stock
    £4.19
  • Paracetamol 500mg Paracetamol 500mg 32 Capsules

    Paracetamol Capsule 500mg are used for the relief of mild to moderate pain and feverish conditions. It can also help to relieve headaches, toothache, and symptoms of cold and influenza. Pack of 32 capsules.

    149 reviews In Stock
    £1.99
  • Solpadeine Max Soluble Solpadeine Max Soluble 24 Tablets

    Solpadeine® Max Soluble Tablets are clinically proven painkillers for the short term treatment of acute moderate pain whenother painkillers have not worked. Wait at least four hours after taking any other painkiller before you take this medicine. Solpadeine® Max Soluble Tablets provide effective pain relief from; Migraine, Headache, Dental Pain, Period Pain, Backache,Arthritic & Rheumatic Pain, Strains & Sprains, Sciatica. Contains Paracetamol, Caffeine and Codeine. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    10 reviews In Stock
    £8.09
  • Almus Ibuprofen & Codeine 200mg/12.8mg Tablets Almus Ibuprofen & Codeine 200mg/12.8mg Tablets 32 Tablets

    Almus Ibuprofen & Codeine 200mg/12.8mg Tablets is indicated in patients older than 12 years of age

    2 reviews In Stock
    £10.99
  • Ibuprofen 400mg Ibuprofen 400mg 84 Tablets

    Ibuprofen reduces inflammation and related pain and so can be used to relieve muscular and rheumatic aches and pains.

    202 reviews In Stock
    £8.49
  • Paracetamol 500mg Paracetamol 500mg 32 Tablets or Caplets

    Paracetamol 500mg Tablets/Caplets helps to bring rapid relief from mild to moderate pain, fever, and the symptoms of cold and flu.

    176 reviews In Stock
    £1.40
  • Paramol Paramol 32 Tablets

    Paramol Tablets are suitable for the treatment of headaches, migraines, fever, period pain, dental pain, and muscular pain. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    67 reviews In Stock
    £11.99
  • Co-codamol 8/500mg Effervescent Co-codamol 8/500mg Effervescent 32 Effervescent Tablets

    Relieve pain without tablets thanks to Co-codamol 8/500mg Effervescent Tablets. With active ingredients paracetamol and codeine phosphate hemihydrate, you can relieve pain that isn't eased by paracetamol, ibuprofen, or aspirin.

    22 reviews In Stock
    £5.59
  • Solpadeine Plus Soluble Solpadeine Plus Soluble 24 Tablets

    Solpadeine Plus Soluble Tablets are used for the short-term relief of moderate pain that is not relieved by other painkillers such as paracetamol or ibuprofen alone. They can be used for migraine, headache, dental pain, period pain, strains & sprains, backache, rheumatic pain and sciatica.

    8 reviews In Stock
    £7.19
  • Migraleve Pink Migraleve Pink 24 Tablets

    Relieve pain and nausea of migraine and prevent an attack developing with Migraleve Pink.This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    84 reviews In Stock
    £10.59
  • Ibuprofen 400mg Ibuprofen 400mg 24 Tablets

    Ibuprofen 400mg Tablets help to relieve mild to moderate pain including rheumatic and muscular pain, sprains and strains, backache, migraine, headache, toothache, period pains, feverishness and symptoms of colds and flu.

    58 reviews In Stock
    £4.59
  • Alka-Seltzer XS Alka-Seltzer XS 20 Tablets

    Relieve mild to moderate pain with Alka-Seltzer XS Effervescent Tablets. Also provide symptomatic relief from joint and muscular aches and pains.

    15 reviews In Stock
    £5.79
  • Syndol Headache Relief Syndol Headache Relief 30 Tablets

    Syndol Headache Relief Tablets - For immediate relief from mild to moderate pain. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    56 reviews In Stock
    £6.79
  • Cryogesic Fine Spray Cryogesic Fine Spray 100ml

    Cryogesic Fine Spray is a fast-acting vapo-coolant spray that provides rapid, transient, topical analgesia for minor invasive procedures, and a source of instant coldness for checking epidural block.

    2 reviews In Stock
    £38.35
  • Aspirin 300mg Aspirin 300mg 32 Tablets

    Aspirin Tablets 300mg are for the relief or treatment of mild to moderate pain including headache,migraine,toothache, neuralgia, sore throat, period pains and aches and pains. Suitable for adults and children over 16 years.

    20 reviews In Stock
    £1.39
  • Ibuprofen Tablets 200mg Ibuprofen Tablets 200mg 24 Tablets

    Ibuprofen Tablets 200mg belong to a group of medicines called nonsteroidal anti-inflammatory drugs (NSAID), which works to reduce inflammation and pain. This medicine helps to reduce discomfort associated with the symptoms of a cold and the flu.

    45 reviews In Stock
    £2.99
  • Migraleve Complete Migraleve Complete 12 Tablets

    Relieve pain and nausea of migraine and revent an attack developing with Migraleve Pink. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    11 reviews In Stock
    £8.39
  • Nurofen Max Strength 684mg for Migraine Nurofen Max Strength 684mg for Migraine 12 Caplets

    Nurofen Migraine Pain is for the effective relief of migraine and headache pain.

    17 reviews In Stock
    £6.09
  • Calpol Six Plus Sugar Free Suspension Calpol Six Plus Sugar Free Suspension 200ml

    CALPOL Six Plus Suspension is a sugar free, strawberry flavoured oral suspension for children aged 6 years onwards. Contains paracetamol. For pain and fever relief. Always read the label.200ml.

    6 reviews In Stock
    £7.99
  • Migraleve Pink Migraleve Pink 12 Tablets

    Relieve pain and nausea of migraine and revent an attack developing with Migraleve Pink. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    15 reviews In Stock
    £7.50
  • Feminax Express for Period Pain Relief Feminax Express for Period Pain Relief 16 Tablets

    Feminax Express Tablets help to deliver fast, effective relief from period pain and cramps when you need an immediate relief.

    11 reviews In Stock
    £4.79
  • Nurofen Long Lasting Pain Relief 300mg Prolonged Release Nurofen Long Lasting Pain Relief 300mg Prolonged Release 24 Capsules

    Nurofen Long Lasting Pain Relief 300mg Prolonged Release Capsules offers effective 12-hour protection from back pain. Their powerful solution helps give lasting relief. They have been specifically designed to slowly release the active ingredient, ibuprofen, at the source of your pain which means they can help ease symptoms and reduce inflammation for up to 12 hours, giving you the freedom to get on with your life.

    34 reviews In Stock
    £7.99
  • Calpol SixPlus Fastmelts Paracetamol Calpol SixPlus Fastmelts Paracetamol 24 Pack

    Calpol Six Plus Fastmelts are strawberry flavoured tablets that are used to relieve pain and / or bring down fever in many conditions including cold and flu, headache, toothache, earache, post-immunisation fever, sore throat and other aches and pains.

    18 reviews In Stock
    £7.59
  • Nurofen Express 400mg Nurofen Express 400mg 20 Liquid Capsules

    Nurofen Express 400mg Liquid Capsules provide double the extra strength in a single filled capsule as the 200mg capsule, and offers effective relief from pain, inflammation and high temperatures.

    21 reviews In Stock
    £10.69
  • Panadol Advance 500mg Panadol Advance 500mg 16 Tablets

    Panadol Advance tablets are familiar, paracetamol based, trusted pain relief tablets that provide fast, effective relief of fever and mild to moderate pain, yet is so gentle on the stomach, it can be taken on an empty stomach.

    36 reviews In Stock
    £2.25
  • Voltarol Joint & Back Pain Relief Gel 2.32% Voltarol Joint & Back Pain Relief Gel 2.32% 50g

    Voltarol Joint & Back Pain Relief 2.32% Gel contains the active substance diclofenac and is used to relieve pain and reduce inflammation and swelling in a number of painful conditions affecting the joints and muscles.

    43 reviews In Stock
    £12.15
  • Ibuleve Maximum Strength Gel 10% Ibuleve Maximum Strength Gel 10% 50g

    Ibuleve Maximum Strength Gel 10% is an anti-inflammatory painkiller for the treatment of a backache, rheumatic or muscular pain, sprains, strains, and neuralgia. It can also be used for pain relief in common arthritic conditions.

    34 reviews In Stock
    £7.69
  • Voltarol Joint & Back Pain Relief Gel 2.32% Voltarol Joint & Back Pain Relief Gel 2.32% 30g

    Voltarol Joint & Back Pain Relief 2.32% Gel contains the active substance diclofenac and is used to relieve pain and reduce inflammation and swelling in a number of painful conditions affecting the joints and muscles.

    22 reviews In Stock
    £9.40
  • Ibuprofen Pain Relief Gel Maximum Strength Ibuprofen Pain Relief Gel Maximum Strength 50g

    Maximum Strength Ibuprofen 10% Gel is for the relief of pain associated with sprains, strains, sports injuries, pain and inflammation associated with backache, rheumatic and muscular pain. Also for the relief of pain of non-serious arthritic conditions.

    38 reviews In Stock
    £5.09
  • Movelat Cream Movelat Cream 125g

    Movelat Cream is an anti-inflammatory and analgesic topical treatment to provide relief from muscular pain and stiffness, sprains and strains, and pain due to rheumatic and non-serious arthritic conditions.

    19 reviews In Stock
    £12.99
  • Anadin Extra Anadin Extra 32 Caplets

    Anadin Extra Caplets contain aspirin, paracetamol and caffeine which all help to provide fast, effective pain relief from headaches, aches and pain.

    73 reviews In Stock
    £5.20
  • Nurofen Ibuprofen 200mg Meltlets Lemon Nurofen Ibuprofen 200mg Meltlets Lemon 12 Tablets

    Nurofen Meltlets offer relief of mild to moderate pain, such as headaches, cold and flu symptoms and muscular pain.

    10 reviews In Stock
    £4.20
  • Calpol Infant Suspension - Sugar Free Calpol Infant Suspension - Sugar Free 200ml

    CALPOL ® Infant Suspension is a sugar-free, strawberry flavoured oral suspension for children relieve the symptoms of fever, colds and flu and other common conditions. For infants 2 months + (weighing over 4kg & not premature). Contains paracetamol. For pain and fever. Always read the label.

    11 reviews In Stock
    £7.00
  • Panadol Extra Advance Compack Panadol Extra Advance Compack 16 Tablets

    Panadol Extra Advance Tablets Compack provides extra effective pain relief from headaches, period pain and the aches & pains associated with colds & flu. Contains paracetamol.

    10 reviews In Stock
    £3.99
  • Paramol Paramol 24 Tablets

    Paramol Tablets are suitable for the treatment of headaches, migraines, fever, period pain, dental pain, and muscular pain. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    14 reviews In Stock
    £9.99
  • Voltarol Osteoarthritis Joint Pain Relief 1.16% Gel Voltarol Osteoarthritis Joint Pain Relief 1.16% Gel 30g

    Voltarol Osteoarthritis Joint Pain Relief 1.16% Gel 30g, brings targeted and localised relief from pain and swelling (inflammation) in muscles, back and neck. It relieves pain to help you get moving again.

    17 reviews In Stock
    £6.29
  • Algesal Local Analgesic Cream Algesal Local Analgesic Cream 50g

    Algesal Local Analgesic Cream is a local analgesic to relieve the symptoms of various muscular and rheumatic pains.

    55 reviews In Stock
    £2.79
  • Movelat Gel Movelat Gel 125g

    Movelat Gel is a mild to moderate anti-inflammatory and analgesic (pain-relieving) preparation which, when applied to the skin, provides relief from muscular pain and stiffness, sprains and strains, and pain due to rheumatic and non-serious arthritic conditions.

    16 reviews In Stock
    £13.59
  • Nurofen for Children Liquid Strawberry Flavour10% off Nurofen for Children Liquid Strawberry Flavour 200ml

    Nurofen for Children is an ibuprofen suspension that starts to work directly at the source of pain and fever to help ease your childs discomfort, fast.

    9 reviews In Stock
    £8.09£8.99
  • 4head Headache Relief Stick5% off 4head Headache Relief Stick 3.6g

    4head Headache Relief Stick is specially designed in a convenient retractable stick dispenser, to be applied directly to the forehead as soon as a headache begins.

    26 reviews In Stock
    £4.74£4.99
  • Biofreeze Pain Relief Gel Biofreeze Pain Relief Gel 118ml

    Biofreeze Pain Relief Gel provides temporary relief of minor aches and pains of muscles and joints.

    14 reviews In Stock
    £10.99
  • Nurofen Ibuprofen 200mg for Headaches & Pain Relief Nurofen Ibuprofen 200mg for Headaches & Pain Relief 96 Tablets

    Nurofen Tablets Ibuprofen 200mg is for the effective relief of headaches, backache, period pain, dental pain, neuralgia, rheumatic pain, muscular pain, migraine, cold & flu symptoms & feverishness.

    59 reviews In Stock
    £11.39
  • Panadol Extra Soluble Panadol Extra Soluble 24 Tablets

    Panadol Extra Soluble Tablets are suitable for headaches, including migraine, backache, rheumatic pain, neuralgia, toothache and period pain. Contains paracetamol.

    21 reviews In Stock
    £5.58
  • Deep Heat Maximum Strength Deep Heat Maximum Strength 35g

    Deep Heat Maximum Strength offers powerful and targeted pain relief for relieving rheumatic pain, back pain, sciatica, and fibrositis with the relaxing benefits of heat therapy.

    12 reviews In Stock
    £4.89
  • Deep Heat Rub Deep Heat Rub 100g

    Deep Heat Rub provides fast relief from muscular aches and pains.

    33 reviews In Stock
    £5.49
  • Radian B Ibuprofen 5% Gel Radian B Ibuprofen 5% Gel 30g

    Radian B Ibuprofen 5% Gel is a non-steroidal anti-inflammatory topical gel for the relief of pain and inflammation in conditions such as backache, rheumatic and muscular pain, sprains, strains and sports injuries.

    12 reviews In Stock
    £3.29
  • Voltarol Osteoarthritis Joint Pain Relief 1.16% Gel Voltarol Osteoarthritis Joint Pain Relief 1.16% Gel 30g | x3 Pack

    Voltarol Osteoarthritis Joint Pain Relief 1.16% Gel 30g Triple Pack, brings targeted and localised relief from pain and swelling (inflammation) in muscles, back and neck. It relieves pain to help you get moving again.

    24 reviews In Stock
    £15.90
  • Ibugel Ibuprofen 5% Gel Ibugel Ibuprofen 5% Gel 100g

    Ibugel Ibuprofen 5% Gel is an anti-inflammatory painkiller that is applied to the skin to relieve backaches, rheumatic or muscular pain, sprains, strains, and neuralgia. It can also be used for pain relief in common arthritic conditions.

    19 reviews In Stock
    £9.59
  • Nurofen Joint & Back 10% Gel Nurofen Joint & Back 10% Gel 40g

    Nurofen 10% Gel is used to treat a number of painful conditions affecting the joints andmuscles such as back pain, rheumatic and muscular pain, sprains, strains and sportsinjuries

    14 reviews Limited Stock
    £7.79
  • Nuromol 200/500mg Nuromol 200/500mg 24 Tablets

    Effective relief from mild to moderate pain, from Nuromol.

    6 reviews In Stock
    £7.50
  • Nurofen Express 200mg Nurofen Express 200mg 30 Liquid Capsules

    Nurofen Express 200mg Liquid Capsules provide extra strength in a single filled capsule and effective relief from pain, inflammation and high temperatures.

    17 reviews In Stock
    £8.19
  • Biofreeze Pain Relief Roll-On Biofreeze Pain Relief Roll-On 89ml

    Biofreeze Pain Relief Roll-On provides temporary relief from minor aches and pains of sore muscles and joints.

    12 reviews In Stock
    £10.89
  • Nurofen Express 200mg Nurofen Express 200mg 16 Liquid Capsules

    Target pain fast with Nurofen.

    6 reviews In Stock
    £4.49
  • Anadin Ultra 200mg Anadin Ultra 200mg 16 Liquid Capsules

    Anadin Ultra 200mg Liquid Capsules contain ibuprofen to give up to 8 hours relief from pain. Suitable for back pain, joint or rheumatic pain, muscle ache, headaches & migraine.

    5 reviews In Stock
    £3.29
  • Cura-Heat Back & Shoulder Cura-Heat Back & Shoulder 3 Heat Pads

    Cura-Heat Back & Shoulder in an adhesive, air-activated heat pack to provide targeted relief to minor muscular and joint aches and pains.

    16 reviews In Stock
    £3.79
  • Deep Heat Patches Deep Heat Patches 4 Patches

    Deep Heat Patches are odourless, non-staining, and are ready to use to provide targeted pain relief to muscular aches and pains, joint stiffness, and backache.

    8 reviews In Stock
    £7.19
  • Nurofen for Children Liquid Strawberry Flavour Nurofen for Children Liquid Strawberry Flavour 100ml

    Nurofen For Children Strawberry works to reduce fever in just 15 minutes and lasts for up to 8 hours, so your child gets a good night's sleep. Nurofen contains 100mg of the active ingredient Ibuprofen.

    9 reviews In Stock
    £4.19
  • Nuromol Dual Action Pain Relief 200/500mg Nuromol Dual Action Pain Relief 200/500mg 16 Tablets

    NUROMOL dual action pain relief tablets 200mg/500mg 16s

    2 reviews In Stock
    £5.49
  • Voltarol Back & Muscle Pain Relief Gel 1.16% With No Mess Applicator Voltarol Back & Muscle Pain Relief Gel 1.16% With No Mess… 100g

    With its triple effect, Voltarol Back and Muscle Pain Relief Gel 1.16% With No Mess Applicator, relieves pain and reduces inflammation. It brings targeted local relief for pain and swelling (inflammation) in muscles, back and neck. The No Mess Applicator allows easy, clean application of the Voltarol Gel directly on the point of pain.

    21 reviews In Stock
    £16.80
  • Alka Seltzer Original Pain Relief Alka Seltzer Original Pain Relief 10 Tablets

    Relieve mild to moderate pain with Alka-Seltzer Original Effervescent Tablets. Also provide symptomatic relief from joint and muscular aches and pains.

    18 reviews In Stock
    £4.50
  • Biofreeze Pain Relief Spray Biofreeze Pain Relief Spray 118ml

    Biofreeze Pain Relief Spray delivers targeted pain relief for minor aches and pains of muscles and joints.

    4 reviews In Stock
    £10.49
  • Sudafed Congestion & Headache Relief Max Strength 16 Years + Sudafed Congestion & Headache Relief Max Strength 16 Years… 16 Capsules

    Sudafed Congestion & Headache Relief Max Strength Capsules can soothe pain and congestion from sinusitis.

    6 reviews In Stock
    £4.45
  • Nurofen Express Ibuprofen 400mg Liquid Nurofen Express Ibuprofen 400mg Liquid 10 Capsules

    Nurofen Express 400mg Liquid Capsules provide extra strength in a single filled capsule and offer effective relief from pain, inflammation and high temperatures.

    6 reviews Limited Stock
    £5.99
  • Nurofen Plus 200mg Nurofen Plus 200mg 24 Tablets

    Nurofen Plus tablets can be used for the short-term relief of rheumatic and muscular pain, backache, migraine, headache, neuralgia, period pain and dental pain. This medicine should not be taken for more than 3 days. If symptoms persist, please see your doctor.

    11 reviews In Stock
    £10.99
  • Deep Heat Rub 67g Deep Heat Rub 67g 67g

    Deep Heat Heat Rub can be massaged into the affected area to help stimulate circulation, relax and oxygenate tense, painful tissue. Treats painful conditions such as rheumatic pain, sciatica, lumbago or fibrositis by providing soothing warmth. Can be used for the treatment of minor sports injuries, and before and after exercise.

    1 review Limited Stock
    £4.49
  • Flarin Ibuprofen 200mg22% off Flarin Ibuprofen 200mg 12 Soft Capsules

    Flarin 12 Soft Capsules contains 200mg of ibuprofen for the relief of joint and muscular pain and flaring joint pain and inflammation. Flarin helps to stop pain, relieve swelling and ease stiffness of the joints. Flarin is as effective as prescription strength ibuprofen for joint pain.

    4 reviews In Stock
    £4.05£5.20
  • Calpol Infant Suspension - Sugar Free Strawberry Calpol Infant Suspension - Sugar Free Strawberry 100ml

    CALPOL Infant Suspension is a sugar free, strawberry flavoured oral suspension for children to help your child feel better and relieve the symptoms of fever, colds and flu and other common conditions.

    16 reviews In Stock
    £4.95
  • Nurofen Express Ibuprofen 256mg Nurofen Express Ibuprofen 256mg 16 Caplets

    Nurofen Express 256mg 16 Caplets get straight to the source of the pain, delivering relief twice as fast as standard caplets.

    8 reviews In Stock
    £3.99
  • Nurofen 200mg Nurofen 200mg 16 Tablets

    Nurofen Tablets Ibuprofen 200mg is for the effective relief of headaches, backache, period pain, dental pain, neuralgia, rheumatic pain, muscular pain, migraine, cold & flu symptoms & feverishness.

    5 reviews Limited Stock
    £2.66
  • Cura Heat Max Cura Heat Max 2 Patches

    Cura-Heat - MAX are maximum sized heat patches, providing up to 24 hours of targeted pain relief to a large area. The patches are especially well-suited to provide relief from acute back pain.

    3 reviews In Stock
    £5.39
  • Snowfire Ointment Stick Snowfire Ointment Stick 18g

    Snowfire Ointment Stick is a solid emollient ointment for dry skin. It can be used by those who are prone to dry skin conditions such as chapped hands & chilblains.

    15 reviews In Stock
    £6.39
  • SolpaOne 1000mg Effervescent SolpaOne 1000mg Effervescent 12 Tablets

    SolpaOne 1000mg an effervescent, single-dose paracetamol tablet ideal for mild to moderate pain relief and for those who have difficulty swallowing pills.

    1 review In Stock
    £5.35
  • Pernaton Gel Pernaton Gel 125ml

    Pernaton Gel is a green lipped mussel extract gel specially formulated to help connective tissue and joint care. It can also benefit sportsmen and sportswomen when used before and after exercise.

    73 reviews In Stock
    £11.89

Get your headache relief from Chemist Direct

How do you treat a headache?

Headaches, whether they are general, migraines or tension related, they are one of the most common ailments to affect us in our everyday lives. But when they do hit, all we want to do is lay down and shut our eyes. Unfortunately, as we are busy working people, we cannot afford such a luxury, so instead, we look for headache cures.

Need a sinus headache relief remedy?

We stock an array of headache cures that work almost immediately after taking, from trusted brands such as Nurofen, Solpadeine and Anadin, so that you can simply get on with your day.

Look to Chemist Direct to relieve your headache relief woes

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