This Thrush Oral Capsule Containing Fluconazole is used for treating fungal infections such as thrush in men and women. It is an effective antifungal treatment that is taken orally. It contains the active ingredient Fluconazole which provides healing for genital thrush and infections of the vagina or penis.
Thrush is a yeast infection called Candida. This lives in your body without any adverse effect. However, if your natural pH balance in your vagina becomes upset, Candida can multiply and develop into a thrush.
Fluconazole is designed to kill the fungi that cause thrush infections. It does this by making holes in the cell membranes. This causes the essential constituents of the fungal cells out and kills the fungi, clearing up the infection.
Thrush Oral Capsule Containing Fluconazole is an effective antifungal treatment you can trust.
Thrush can manifest itself in several key symptoms such as:
The fluconazole works to kill the fungi, specifically Candida Albicans Fungi, that causes thrush. It does this by interfering with the membranes of these cells by preventing them from producing Ergosterol. This causes holes to appear, killing the fungi effectively and quickly.
Please note: this treatment is not suitable for oral thrush.
Always take this medicine exactly as described in this leaflet or as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure. You should read the instructions on the pack. Thrush Oral 150 mg Capsule should only be taken by mouth.
The whole course of treatment for vaginal thrush is one capsule which you take by mouth. Take the capsule with a glass of water. Some women notice an improvement after one day and the thrush should clear up after 2 days. If symptoms persist for more than 7 days, consult your doctor. If after treatment with Thrush Oral 150 mg Capsule you have a re-occurrence of thrush, you should only take this product again if it has been more than 7 days since your last treatment. If you experience a thrush infection more than twice over a six month period, consult your doctor.
Remember that Fluconazole can only treat thrush. It cannot treat other infections of the genitals. If you still have any sort of symptoms one or two days after you have taken Fluconazole, you should visit your doctor in case you have another type of infection.
If you take more Thrush Oral 150 mg Capsule than you should If you (or someone else) swallow a lot of capsules at the same time, or you think a child has swallowed any of the capsules, contact your nearest hospital casualty department or your doctor immediately
Do not take Thrush Oral 150 mg Capsule
• if you are allergic to Fluconazole, to other medicines you have taken to treat fungal infections or to any of the other ingredients of this medicine. The symptoms may include itching, reddening of the skin or difficulty in breathing • if you are taking astemizole, terfenadine (antihistamine medicines for allergies) • if you are taking cisapride (used for stomach upsets) • if you are taking pimozide (used for treating mental illness) • if you are taking quinidine (used for treating heart arrhythmia) • if you are taking erythromycin (an antibiotic for treating infections) • if you are taking amiodarone (used for treating uneven heartbeats 'arrhythmias').
Warnings and precautions Talk to your doctor or pharmacist before taking Fluconazole • if you have liver or kidney problems • if you suffer from heart disease, including heart rhythm problems • if you have abnormal levels of potassium, calcium or magnesium in your blood • if you develop severe skin reactions (itching, reddening of the skin or difficulty in breathing) • if you develop signs of 'adrenal insufficiency' where the adrenal glands do not produce adequate amounts of certain steroid hormones such as cortisol (chronic, or long lasting fatigue, muscle weakness, loss of appetite, weight loss, abdominal pain) • if the fungal infection does not improve, as alternative antifungal therapy may be needed • if you have ever developed a severe skin rash or skin peeling, blistering and/or mouth sores after taking Thrush Oral 150 mg Capsule.
Serious skin reactions including drug reaction with eosinophilia and systemic symptoms (DRESS) have been reported in association with Thrush Oral 150 mg Capsule treatment.
Stop taking Thrush Oral 150 mg Capsule and seek medical attention immediately if you notice any of the symptoms related to these serious skin reactions.
Other medicines and Thrush Oral 150 mg Capsule: Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines. Tell your doctor immediately if you are taking astemizole, terfenadine (an antihistamine for treating allergies) or cisapride (used for stomach upsets) or pimozide (used for treating mental illness) or quinidine (used for treating heart arrhythmia) or erythromycin (an antibiotic for treating infections) as these should not be taken with Fluconazole
There are some medicines that may interact with Fluconazole. Make sure your doctor knows if you are taking any of the following medicines: • rifampicin or rifabutin (antibiotics for infections) • alfentanil, fentanyl (used as anaesthetic) • amitriptyline, nortriptyline (used as anti-depressant) • amphotericin B, voriconazole (anti-fungal) • medicines that thin the blood to prevent blood clots (warfarin or similar medicines) • benzodiazepines (midazolam, triazolam or similar medicines) used to help you sleep or for anxiety • carbamazepine, phenytoin (used for treating fits) • olaparib (used for treating ovarian cancer) • nifedipine, isradipine, amlodipine, felodipine and losartan (for hypertension - high blood pressure) • ciclosprin, everolimus, sirolimus or tacrolimus (to prevent transplant rejection) • cyclosphosphamide, vinca alkaloids (vincristine, vinblastine or similar medicines) used for treating cancer • halofantrine (used for treating malaria) • statins (atorvastatin, simvastatin and fluvastatin or similar medicines) used for reducing high cholesterol levels • methadone (used for pain) • celecoxib, flurbiprofen, naproxen, ibuprofen, lornoxicam, meloxicam, diclofenac (Non-Steroidal Anti-lnflammatory Drugs (NSAID)) • oral contraceptives • prednisone (steroid) • zidovudine, also known as AZT; saquinavir (used in HIVinfected patients) • medicines for diabetes such as chlorpropamide, glibenclamide, glipizide or tolbutamide • theophylline (used to control asthma) • vitamin A (nutritional supplement) • ivacaftor (used for treating cystic fibrosis) • amiodarone (used for treating uneven heartbeats 'arrhythmias') • hydrochlorothiazide (a diuretic) • ibrutinib (used for treating blood cancer) • tofacitinib (used for treating rheumatoid arthritis).
Thrush Oral 150 mg Capsule with food and drink You can take your medicine with or without a meal at any time of day. Take the capsule with a glass of water.
Like all medicines, this medicine can cause side effects, although not everybody gets them. These can be seen even with a single dose of 150 mg. A few people develop allergic reactions although serious allergic reactions are rare. If you get any side effects, talk to your doctor or pharmacist. This includes any possible side effects not listed in this leaflet. If you get any of the following symptoms, tell your doctor immediately: • sudden wheezing, difficulty in breathing or tightness in the chest • swelling of eyelids, face or lips • itching all over the body, reddening of the skin or itchy red spots • skin rash • severe skin reactions such as a rash that causes blistering (this can affect the mouth and tongue).
Thrush Oral 150 mg Capsule (Fluconazole) may affect your liver. The signs of liver problems include: • tiredness • loss of appetite • vomiting • yellowing of your skin or the whites of your eyes (jaundice). Thrush Oral 150 mg Capsule (Fluconazole) may affect your adrenal glands and the levels of steroid hormones produced. The signs of adrenal problems include: • tiredness • muscle weakness • loss of appetite • weight loss • abdominal pain. If any of these happen, stop taking Fluconazole and tell your doctor immediately:
Stop taking Thrush Oral 150 mg Capsule and seek medical attention immediately if you notice any of the following symptoms: • Widespread rash, high body temperature and enlarged lymph nodes (DRESS syndrome or drug hypersensitivity syndrome).
Other side effects: Additionally, if any of the following side effects gets serious, or if you notice any side effects not listed in this leaflet, please tell your doctor or pharmacist. Common side effects (may affect up to I in 10 people) are: • headache • stomach discomfort, diarrhoea, feeling sick, vomiting • increase in blood tests of liver function • rash.
Uncommon side effects (may affect up to I in 100 people) are: • reduction in red blood cells which can make skin pale and cause weakness or breathlessness • decreased appetite • inability to sleep, feeling drowsy • fits, dizziness, sensation of spinning, tingling, pricking or numbness, changes in sense of taste • constipation, difficulty in digestion, wind, dry mouth • muscle pain • liver damage and yellowing of the skin and eyes (jaundice) • wheals, blistering (hives), itching, increased sweating • tiredness, general feeling of being unwell, fever. Rare side effects (may affect up to I in 1,000 people) are: • lower than normal white blood cells that help defend against infections and blood cells that help to stop bleeding • red or purple discoloration of the skin which may be caused by low platelet count, other blood cell changes • blood chemistry changes (high blood levels of cholesterol, fats) • low blood potassium • shaking • abnormal electrocardiogram (ECG), change in heart rate or rhythm • liver failure • allergic reactions (sometimes severe), including widespread blistering rash and skin peeling, severe skin reactions, swelling of the lips or face • hair loss. Frequency not known, but may occur (cannot be estimated from the available data): • hypersensitivity reaction with skin rash, fever, swollen glands, increase in a type of white blood cell (eosinophilia) and inflammation of internal organs (liver, lungs, heart, kidneys and large intestine) (Drug Reaction or rash with Eosinophilia and Systemic Symptoms (DRESS)).
Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App store. By reporting side effects you can help provide more information on the safety of this medicine.
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