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J Collis Brownes Mixture

J Collis Browne's Mixture J Collis Browne's Mixture

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J Collis Browne's Mixture provides effective, warming relief from diarrhoea and stomach upsets, as well as dry and unproductive coughs.

J Collis Browne's Mixture

What is J Collis Browne's Mixture?

J Collis Browne's Mixture is a treatment that can be used to relieve symptoms of diarrhoea, stomach upsets, and coughs.

How Does J Collis Browne's Mixture Work? 

It contains a low dose of anhydrous morphine, which helps the digestive tract to slow down the contractions of the intestine and allow more water to be absorbed from undigested food.

Peppermint oil is added to relax the spasms in the gut that cause stomach pains and upsets linked to diarrhoea.

How does J Collis Browne's Mixture Relieve Coughs?

J Collis Browne's Mixture is also used to relieve dry and unproductive coughs by suppressing the reflexes which produce coughing.

Approved by Anju Gill -Pharmacist on the 21/05/2021.
For more information, view our medical team

Take this medicine by mouth.

Elderly and debilitated patients Use with caution; a reduced dose can be recommended by a doctor.

 For Diarrhoea Adults and children over 12 years • Take two or three 5ml spoonfuls (10-15ml) every 4 hours up to a maximum of three doses.

For coughs Adults and children over 12 years • Take one or two 5ml spoonfuls (5-10ml) every 4 hours.

 Children under 12 years Do not give to children under 12 years.


 If your symptoms persist you should ask your doctor for advice. If you take too much If you accidentally take too much, see a doctor straight away. Take the pack with you to show which medicine you have swallowed. If you forget a dose Take the next dose as soon as you remember.

 Do not take a double dose. You can then carry on with the normal dose at the correct time

• This medicine relieves the symptoms of coughs and diarrhoea in adults and children over 12 years. Do not take…. • If you have breathing problems. • Or give to children under 12 years. • Avoid drinking alcohol while taking this medicine. See section 2. • Elderly and debilitated patients: ask your doctor for advice, a lower dose might be more suitable. • Different doses are needed depending on whether you take this medicine for a cough or for diarrhoea Do not use the medicine if you or your child have…. • An allergy to any of the ingredients listed in section 6, or to menthol. • Shallow breath or breathing difficulties. • Heart problems. • A head injury or persistent headache. • An asthma attack. • Taken MAOIs (monoamine oxidase inhibitors) for depression within the last two weeks. • Liver disease. • Unconsciousness. • Epilepsy or fits. • A blocked intestine or inflammation of your colon or rectum. • Inflammation of the pancreas. • Severe abdominal pain. • An addiction to alcohol. • Phaeochromocytoma (a rare tumour of the adrenal glands). • Or your child is under 12 years old.

 Talk to your doctor if you or your child have…. • Kidney or liver problems. • Low blood pressure. • Shock. • Myasthenia gravis. • Prostate problems. • Problems with your bile system. • Irregular heartbeat. • A history of asthma, or lung disease including chronic bronchitis. • An under active thyroid gland. • Adrenal gland problems. • An addiction to drugs such as painkillers or morphine. • Or are elderly, or weak as you may react differently to this medicine. Talk to your doctor or pharmacist if you or your child are taking…Any tranquillisers/sedatives (e.g. diazepam, lorazepam). • Any antidepressants (e.g. MAOIs, SSRIs amitriptyline). • Any sleeping tablets (e.g. temazepam, promethazine, amobarbital). • Any medicine for mental illness (e.g. chlorpromazine, haloperidol). • Any medicine to treat epilepsy (e.g. carbamazepine, phenytoin, gabapentin). • Medicines used to treat blood clots (e.g. clopidogrel, prasugrel, ticagrelor) as these may have delayed and decreased effect when taken together with morphine • Medicines to thin the blood (e.g. warfarin). • Medicine for high blood pressure (e.g. esmolol). • Alcohol. • Cimetidine for a stomach ulcer. • Metoclopramide or domperidone for nausea and vomiting. • Baclofen a muscle relaxant. • Sodium oxybate for chronic daytime sleepiness. • Antibiotics (e.g. rifampicin, ciprofloxacin). • Antivirals (e.g. ritonavir). • Antihistamines with sedative effects.

 If you are having a general anaesthetic in hospital, tell the doctors if you have taken J.Collis Browne's Mixture as it may affect the anaesthetic. Concomitant use of this product and sedative medicines such as benzodiazepines or related drugs increases the risk of drowsiness, difficulties in breathing (respiratory depression), coma and may be lifethreatening. Because of this, concomitant use should only be considered when other treatment options are not possible. However if your doctor does prescribe this product together with sedative medicines the dose and duration of concomitant treatment should be limited by your doctor. Please tell your doctor about all sedative medicines you are taking, and follow your doctor’s dose recommendation closely. It could be helpful to inform friends or relatives to be aware of the signs and symptoms stated above. Contact your doctor when experiencing such symptoms

Pregnant or breastfeeding…. This product should not be used in pregnancy or whilst breastfeeding unless recommended by a doctor.

Driving and using machines.... This medicine may cause drowsiness. If you are affected do not drive or operate machinery. The medicine can affect your ability to drive as it may make you sleepy or dizzy. • Do not drive while taking this medicine until you know how it affects you. • It is an offence to drive if this medicine affects your ability to drive. • However, you would not be committing an offence if: ° The medicine has been prescribed to treat a medical or dental problem and ° You have taken it according to the instructions given by the prescriber or in the information provided with the medicine and ° It was not affecting your ability to drive safely. . Important information about some of the ingredients This medicine contains 119mg of alcohol (ethanol) in each 5ml dose which is equivalent to 3% v/v. The amount in 5ml of this medicine is equivalent to less than 3ml of beer and 2ml of wine. The small amount of alcohol in this medicine will not have any noticeable effects.

Like all medicines J. Collis Browne’s Mixture can have side effects, although these don’t affect everyone. If you notice any of the following side effects you must stop taking this medicine immediately and see a doctor straight away. Important side effects • Allergic reactions (rash, hives, itching, wheezing). • Drowsiness or difficulty sleeping. • Difficulty in breathing. • Muscle twitching, spasms or muscle rigidity. • Dizziness or fainting. • Changes in heart rate or palpitations (awareness of your heartbeat). • Fits (seizures). • Change in eyesight e.g. blurred vision, pinpoint pupils, unusual eye movement. • Confusion, mood changes, feeling restless, excited or agitated. Hallucinations (seeing or hearing things). • Severe abdominal or back pain, e.g. caused by bile duct problems.

 Other possible side effects are: • Feeling sick or being sick. • Constipation. • Difficulty in passing urine or reduced amounts of urine when you do urinate. • Dry mouth, changes in taste. • Loss of appetite. • Stomach ache, indigestion. • Sweating. • Headache • A flushed face. • Signs of swelling or fluid retention. • Lower or higher blood pressure. • Low body temperature. • Tingling or numbness. • Addiction and dependence. • Loss of sex drive. • No menstrual periods. • Feeling generally unwell. • An increased sensitivity to pain. If you notice these or any other side effect not included above, stop use and tell your doctor or pharmacist. They will tell you what to do.

Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at or search for 'MHRA Yellow Card' in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.

The active ingredients per 5ml are: morphine hydrochloride equivalent to 1.0mg anhydrous morphine, peppermint oil 1.5 microlitres.

 The other ingredients are: ethanol (alcohol), benzoic acid (E210), capsicum tincture, caramel (E150), menthol, citric acid (E330), hypromellose, sorbitol solution (E420), treacle (containing sucrose and fructose), purified water.


The views expressed are those of our customers. If you require advice on a condition or treatment, please contact your doctor or pharmacist. For any questions regarding the products, please contact us. Please note: due to advertising regulations, not all product reviews can be displayed. Please be advised that people respond to products differently and you should always read the label.

 rated J Collis Browne's Mixture as:
5.00 stars

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5.00 stars


Very happy to be able to get this as it can be difficult to find.

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5.00 stars

Excellent for upset tummy

Very good service from Chemist Direct and arrived in good time

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4.00 stars

Efficient service

Item ordered arrived within time and well wrapped. Good service from Chemist Direct

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 rated J Collis Browne's Mixture as:
5.00 stars

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5.00 stars

Warming relief

It's the best for me that I've found and have used it for years but never for a cough so can't comment on that.

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