Nitrolingual Pumpspray 200 Dose provides relief in less than a minute to Angina sufferers, whenever and wherever they need it.
Angina Pectoris is the medical term for chest pain or discomfort usually due to coronary artery disease (CAD). Angina is a symptom of a condition called myocardial ischemia. This symptom is felt when the heart muscle doesn’t get as much blood or oxygen as it needs, usually because the arteries have become narrowed or blocked. When this happens, it can cause uncomfortable pressure, fullness, squeezing, or pain in the centre of the chest. Discomfort also may be felt in the neck, jaw, shoulder, back, or arm.
Sometimes angina can be accompanied by shortness of breath, nausea, dizziness, or tiredness. Some people may break into a cold sweat, or feel their heart pounding. The discomfort usually develops gradually, without a sudden sharp pain. Without treatment, the pain can subside within about 20 minutes.
Fast Pain Relief with Nitrolingual Pump Spray:
In one study, 69% of patients reported pain relief within 60 seconds, compared to 38% of patients who experienced relief within 1 minute when using Nitroglycerin tablets.
Potent and Reliable for 24 Months:
Long shelf life from date of manufacture helps to ensure that Nitrolingual Pump Spray works when you need it. With a 2-year shelf life from the manufacture, Nitrolingual Pump Spray will be reliable and potent when you need it. And with the Pump Spray, there are no concerns regarding loss of potency due to light, moisture or handling.
2 convenient bottle sizes: a 60-metered spray bottle travelling pocket size and a 200-metered spray bottle.
Simple, Easy to Use and Reliable Spray:
Just one spray on or under the tongue provides a metered 0.4mg dose. When angina strikes, it is often sudden and unexpected, causing fear or even panic. Some patients may have difficulty removing small tablets from the packaging when they are in the midst of dealing with an attack. It can also be hard to remember to check expiration dates when time is of the essence.
More Patients Reported no Headache in One Study:
58% of patients taking Nitroglycerin lingual spray reported no headaches when compared with 39% of patients taking Nitroglycerin tablets. One of Nitroglycerin’s side effects is headaches. In this particular study, patients reported experiencing fewer and less severe headaches with Nitroglycerin lingual spray, as opposed to tablets.
Dosage Always take this medicine exactly as described in this leaflet or as your doctor, pharmacist or nurse has told you. Check with your doctor, pharmacist or nurse if you are not sure. The spray is meant for use under your tongue and is not meant to be inhaled. It is recommended to spray one or two puffs under your tongue. If symptoms do not resolve, you can repeat this at 5 minute intervals for a maximum of three puffs. If, after that, your symptoms have still not resolved, please seek immediate medical attention. The spray should work quickly and last about half an hour.
Method of administration Before you use a new bottle of Nitrolingual®, spray the first puff into the air to get the pump working properly. You must also do this if you have not used the pump for a week or more. Get used to the feel of the grooved button in case you need to use the pump in the dark. 1. Rest or sit quietly, as you may feel faint or dizzy otherwise, particularly if you are elderly. 2. Hold the bottle upright with your finger on the button. You don’t need to shake the bottle. 3. Open your mouth and put the bottle next to your chin (see picture). 4. Press the button firmly so that the puff of medicine goes under your tongue (see picture). Close your mouth. 5. Do not breathe in while you are taking the puff of medicine. Keep the spray with you at all times. Through the side of the bottle you can see how much spray you have left. Make sure that you get a new spray before the old one runs out. Always keep a spare. Talk with your doctor about how long you should keep taking Nitrolingual®.
If you take more Nitrolingual® than you should If you take too many puffs you may notice more severe and pronounced side effects , for example, you may get a bad headache, blurred vision, feel flushed or feel that your heart is beating more slowly. You may also feel faint, sweaty, breathless, weak, restless and feel sick or be sick, or notice a bluish tinge to your lips or a bluish colouration of the skin. In very rare cases you may develop methaemoglobinaemia (a disorder of the red blood cells). If any of these effects persist contact your doctor or pharmacist.
If you forget to take Nitrolingual® Do not take a double dose to make up for a forgotten dose.
If you stop taking Nitrolingual® Do not stop taking Nitrolingual® without the advice of your doctor. If you have any further questions on the use of this medicine, ask your doctor or pharmacist or nurse
Warnings and precautions
Talk to your doctor, pharmacist or nurse before taking Nitrolingual® • if you are in the early stages of an eye condition called glaucoma (where there is raised pressure within the eye) • While taking Nitrolingual®, tell your doctor if the spray does not stop the pain; or if the spray usually works, but this time the pain lasts longer (half an hour or more), or feels different or worse than usual. • if you have aortic and/or mitral stenosis (a narrowing of the opening to the heart aortic or mitral valve) • if you feel dizzy when you sit or stand upright suddenly • if you have cerebrovascular disease (brain disorders relating to disease of the blood vessels supplying the brain) • if you have pericardial tamponade (compression of the heart caused by blood or fluid accumulation in the space between the heart muscle and the outer covering of the heart) • if you have constrictive pericarditis (inflammation and swelling of the covering of the heart) • low blood oxygen in lung disease or pulmonary heart disease (enlargement of the right ventricle of the heart) • if you have had a heart attack • if you have left ventricular hypertrophy (thickening of the muscle of the left ventricle of the heart) associated with aortic stenosis (narrowing of the opening of the aortic heart valve) • if you have moderate to severe valvular aortic stenosis (narrowing of the opening of the aortic heart valve)
Other medicines and Nitrolingual® Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines. This is important as using more than one medicine at the same time can strengthen or weaken the effect of the medicines.
Your doctor may need to take special care or change the dose. This is especially important for: • medicines for the treatment of erectile dysfunction or hypertension of arterial lung vessels (see ‘Do not take Nitrolingual®’) • other medicines which can lower blood pressure, such as beta-blockers, calcium channel blockers and neuroleptics, vasodilators, anti-hypertensives, diuretics, tricyclic antidepressants, sapropterin • anti-blood-clotting drugs such as heparin • N-acetyl-cysteine If you use Nitrolingual® very often or if you regularly use other nitrates, the pain relief you receive may be less. During use with dihydroergotamine (DHE) (used to treat migraines), Nitrolingual® may lead to an increase in DHE levels, thereby increasing blood pressure. Nitrolingual® with alcohol If you drink alcohol before using Nitrolingual®, you may feel dizzy or faint due to low blood pressure.
Pregnancy, breast-feeding and fertility Tell your doctor if you become pregnant while you are taking Nitrolingual®. You should use Nitrolingual® only after discussing with your doctor the potential benefits to you versus any potential risks to your unborn child. It is not known whether glyceryl trinitrate passes into human breast milk. You should ask your doctor for advice if you are breast-feeding. There is no sign of a harmful effect with respect to fertility.
Driving and using machines You should wait at least five minutes after using the spray before driving or using machinery. If you feel faint, dizzy or unwell, wait until you feel better. You should be particularly careful if you have just started using Nitrolingual®, if you have changed your dosage or if you drink alcohol.
Like all medicines, this medicine can cause side effects, although not everybody gets them. The frequency of side effects is classified into the following categories:
Very common: may affect more than 1 in 10 people Common: may affect up to 1 in 10 people
Uncommon: may affect up to 1 in 100 people
Rare: may affect up to 1 in 1,000 people
Very rare: may affect up to 1 in 10,000 people
Not known: frequency cannot be estimated from the available data
The following side effects have been reported: Very common: headache Common: decreased blood pressure, which can also occur on standing up; weakness; dizziness; drowsiness; increased heart rate Uncommon: fainting; worsened angina symptoms; slowing of the heart rate; bluish colouration of the skin; facial flushing; circulatory collapse (failure of the blood circulation); nausea; vomiting; allergic skin rash; hypersensitivity. Very rare: cerebral ischaemia (decreased blood flow to the brain); methaemoglobinaemia (a disorder of the red blood cells); restlessness; difficulty breathing; skin rash Not known: tongue swelling (due to an allergic reaction); tongue blistering
Reporting of side effects If you get any side effects, talk to your doctor, pharmacist or nurse. This includes any possible side effects not listed in this leaflet. You can also report side effects directly via the Yellow Card Scheme at: www.mhra.gov.uk/yellowcard or search for MHRA Yellow Card in the Google Play or Apple App Store. By reporting side effects you can help provide more information on the safety of this medicine.
What Nitrolingual® contains The active substance is GTN.
Each puff of spray contains 400 micrograms of GTN. The other excipients are medium-chain triglycerides, ethanol (absolute), glycerol monocaprylocaprate, peppermint oil, (S)-sodium lactate and (S)-lactic acid.
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I was pleased with the level of service particularly the care taken to ensure that this was the correct medication for me and that I had been diagnosed by a Doctor. I will definitely come back when I need anything else.
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