is used for vaccination of cows and heifers to protect their foetuses against infection with Bovine Viral Diarrhoea (BVD) virus inside the cow's womb. Bovilis BVD has been proven to prevent unborn calves from becoming persistently infected (PI). This is most important as PI calves either die soon after birth or act as a source of infection for the rest of the herd. Infecting the rest of the herd may lead to abortions, reduced milk yield and increased return to service, poorer pregnancy rates, mastitis, coughing and other problems in cows and the creation of more PI calves.
Bovilis BVD is an inactivated vaccine containing an equivalent of 7.7 log10 TCID50 per dose of cytopathogenic BVD virus strain C86. The virus is grown in cell culture, inactivated with beta-propiolactone, and adsorbed onto an aluminium salts adjuvant. The vaccine contains methyl parahydroxybenzoate as a preservative and traces of antibiotics and calf serum as remnants from the antigen production.
For active immunisation of cows and heifers to protect the foetus against transplacental infection with Bovine Viral Diarrhoea virus.
Bovilis BVD containsan inactivated antigen of cytopathogenic BVD virus strain C86. Bovilis BVD may only be prescribed and administered by your veterinary surgeon from whom advice should be sought.
Foetal protection has been demonstrated at 6 months post vaccination and can therefore be expected if the primary immunisation has been completed 4 weeks before the start of the gestation. If a herd is vaccinated on the same day, then individuals that are not about 4 weeks pre-gestation may not be protected against foetal infection. Where this is the case, whole herd re-vaccination should be undertaken every 6 months.
BVD challenge data in non-pregnant animals shows protection against cell-free viraemia 12 months after primary vaccination.
A good immune response is reliant upon the reaction of an immunogenic agent and a fully competent immune system. Immunogenicity of the vaccine will be reduced by poor storage or inappropriate administration. Immunocompetence of the animal may be compromised by a variety of factors including poor health, nutritional status, genetic factors, concurrent drug therapy and stress.