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Malarone Tablets (Atovaquone Proguanil)


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Malarone Tablets are also known as Atovaquone Proguanil. Malarone is used for the prevention and treatment of malaria. It is particularly suitable for short trips to areas of the world which have become highly chloroquine-resistant. We can only supply this prescription medication if you have a valid UK prescription.

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Malarone Tablets (Atovaquone Proguanil): Malarone contains two medicines - atovaquone and proguanil hydrochloride. It is used to prevent or treat certain types of malaria. It works by killing the parasites that cause malaria. It is also used to prevent malaria in people who are in areas where there is an increased risk of getting malaria.

What is Malarone?

It could take just one bite from one infected mosquito to get malaria, a serious and sometimes fatal disease. Infected mosquitoes are not just found in the jungle - they can be almost anywhere: the beach, the resort's pool, even inside your hotel room. MALARONE gives you the protection you need almost anywhere you travel. Before your next trip, talk to your doctor about MALARONE.

Malarone is proven to be an effective treatment

Malarone is 98% effective in preventing infection with Plasmodium falciparum, the parasite species that is responsible for most malaria deaths. It is approved for use, even in areas where chloroquine resistance has been reported. MALARONE has been recommended by the Centers for Disease Control and Prevention (CDC) as an option for the prevention of P. falciparum malaria. MALARONE works by defending your body against infection in both your liver and blood where MALARONE then kills the malaria parasites.

Causes of Malaria

Malaria is spread from the bite of a mosquito. When a mosquito bites an infected person, it ingests the malaria parasites found in that person's blood. After one week or more, the mosquito can spread the parasite to other people. After a bite from an infected mosquito, the parasite enters the person's bloodstream and travels to the liver where it grows and multiplies. During this time when the parasite is in the liver, there are no visible symptoms and the victim doesn't feel sick.

The parasite may stay in the liver for a period as short as 8 days or as long as several months to years. After it leaves the liver, it enters red blood cells and continues to grow and multiply. The red blood cells burst, freeing the parasites to attack other red blood cells. It is during this time that symptoms of malaria may begin to surface.

Convenient Dosing That Fits Easily Into Your Travel Plans

MALARONE provides easy, once-daily dosing so you can concentrate on your trip, not your treatment.

MALARONE dosing begins only 2 days before

Malarone Tablets (Atovaquone Proguanil): Always take Malarone exactly as your doctor has told you.

Check with your doctor or pharmacist if you are not sure. Take Malarone with food or a milky drink, where possible. It is best to take Malarone at the same time each day.

To treat malaria

The usual dose for adults is 4 tablets once a day for 3 days.

Not for children, talk to your doctor. Not recommended for preventing malaria in children, or in adults who weigh less than 40 kgs.

To prevent malaria in adults:

  • start taking Malarone 1 to 2 days before travelling to an area which has malaria
  • continue taking it every day during your stay
  • continue taking it for another 7 days after your return to a malaria-free area.

For children the dose depends on their bodyweight:

  • 11-20 kg – 1 tablet once a day for 3 days
  • 21-30 kg – 2 tablets once a day for 3 days
  • 31-40 kg – 3 tablets once a day for 3 days
  • over 40 kg – dose as for adults.

Not recommended for treating malaria in children who weigh less than 11 kgs. For children who weigh less than 11 kgs talk to your doctor. There may be a different type of Malarone tablet available in your country.

Special warnings and precautions for use of Malarone Tablets (Atovaquone Proguanil):

  • Persons taking Malarone for prophylaxis or treatment of malaria should take a repeat dose if they vomit within 1 hour of dosing.
  • In the event of diarrhoea, normal dosing should be continued. Absorption of atovaquone may be reduced in patients with diarrhoea or vomiting, but diarrhoea or vomiting was not associated with reduced efficacy in clinical trials of Malarone for malaria prophylaxis. However, as with other antimalarial agents, subjects with diarrhoea or vomiting should be advised to continue to comply with personal protection measures (repellants, bednets). 
  • In patients with acute malaria who present with diarrhoea or vomiting, alternative therapy should be considered. If Malarone is used to treat malaria in these patients, parasitaemia should be closely monitored. 

You should carefully read all product packaging and labels prior to use

Possible Side Effects from taking Malarone Tablets (Atovaquone Proguanil): Dizziness has been reported. Patients should be warned that if affected they should not drive, operate machinery or take part in activities where this may put themselves or others at risk.

Malarone Tablets (Atovaquone Proguanil) contains:

  • atovaquone and proguanil hydrochloride
  • hypromellose
  • low substituted hydroxypropyl cellulose
  • macrogol 400
  • magnesium stearate
  • microcrystalline cellulose
  • poloxamer 188
  • polyethylene glycol 8000
  • povidone K30
  • red iron oxide (E172)
  • sodium starch glycollate (type A)
  • titanium dioxide (E171)
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