Lariam (Mefloquine) Tablets
1 (Prescription Only)
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Lariam (Mefloquine) Tablets contains 250 mg of the active ingredient, mefloquine. Lariam is an anti-malarial and it is used in both the prevention and treatment of malaria. Mefloquine works by attacking the parasites once they have entered the red blood cells. It kills the parasites and prevents them from multiplying further.
Lariam (Mefloquine) Tablets: Lariam is an anti-malarial. It contains the active ingredient mefloquine. It is is used for the treatment of malaria and to help prevent you from catching malaria.
What is Malaria?
Malaria is a life threatening disease and a major health risk for travellers visiting tropical countries. It occurs when small parasites are passed from one person to another by the bites of certain mosquitoes. The tablets are especially useful if you are travelling to countries where there is a type of malaria which is particularly difficult to treat. No single medicine is effective against all malaria parasites. The choice of a particular medicine depends on the sensitivity of the malaria parasites found in the area to be visited. Your doctor will advise you whether Lariam is suitable for the area to which you wish to go.
To help minimise your chance of catching the disease it is important that you read this information carefully. Ask your doctor to explain anything you do not understand.
Lariam (Mefloquine) Tablets: Always take the tablets as instructed by your doctor. This will depend on whether you are taking the tablets for prevention or treatment of malaria. Take the tablets with plenty of water, and preferably with food. Swallow the tablets whole, do not suck or chew them. If you take too many tablets or someone else accidentally takes your medicine, contact your doctor, pharmacist or nearest hospital straight away.
Please read the following section if you are taking the tablets to help prevent you from catching malaria.
- The tablets should be taken once weekly, always on the same day.
- You should start taking the tablets at least 1 week and up to 2 - 3 weeks before departure. You should continue taking the tablets throughout your stay and for 4 weeks after your return. If you forget to take a dose, take one as soon as you remember, then go on as before.
- For effective prevention you must take the full course of tablets.
- No anti-malarial tablets are completely effective. Malaria can occur during or after preventative medication. If you develop a fever or flu-like symptoms during your travels or within 2 to 3 months after you leave the malarious area, check with a doctor immediately.
Below is an example which gives the recommended dose for a 2-week stay in an area where malaria is present:
at least one week
one tablet weekly
- week 2 - dose = 1
- week 3 - dose = 1
- week 4 - dose = 1
- week 5 - dose = 1
- week 6 - dose = 1
- week 7 - dose = 1
A pack of 8 tablets is enough to help prevent you from catching malaria if you are staying for 3 weeks in an area where malaria is present and if you start taking the tablets 1 week before departure. If your stay is longer than 3 weeks or if your doctor has advised that you should start taking your tablets 2 to 3 weeks before departure, you will need a second pack.
The tablets are not recommended for children under 3 months of age, i.e., those who weigh less than 5kg (11lbs). For children over this weight, the dose is shown in the table below. The tablets can be divided by breaking along the score lines. As in adults, the dose should be taken once weekly on the same day, and continued for 4 weeks after return.
- Weight: 5 - 19kg (11 - 42lbs) Age: (Approx) 3 months - 5 years Dose: ¼ tablet
- Weight: 20 - 30kg (44 - 66lbs) Age: (Approx) 6 - 8 years Dose:½ tablet
- Weight: 31 - 45kg (68 - 99lbs) Age: (Approx) 9 - 14 years Dose:¾ tablet
Lariam (Mefloquine) Tablets:
When Lariam should not be used:
- If you suffer from or have ever suffered from fits, mental complaints or severe changes of mood (such as depression), you should not take Lariam for the prevention of malaria.
- If you have severe liver problems.
- If you are pregnant or breast-feeding, unless your doctor tells you to take Lariam.
- If you are allergic to Lariam, any of the ingredients it contains or to similar medicines such as quinine or chloroquine.
- If you are also taking any other anti-malarial medicines such as quinine, quinidine or chloroquine.
- If you have recently (in the last 3 days) received an oral vaccine to help prevent you from catching typhoid or similar diseases as taking Lariam may stop the vaccine from working properly.
When should you be extra careful while taking Lariam?
Make sure your doctor knows if you:
- have a history of psychiatric illness
- have heart trouble
- are taking any medicines for heart trouble, high blood pressure; blood clotting disorders or diabetes; antihistamines for allergy; tricyclic antidepressants; phenothiazines, used for treatment of some psychiatric disorders, or any medicine for the treatment of epilepsy (e.g. sodium valproate, carbamazepine, phenobarbital, phenytoin).
- have kidney problems
- If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine
You should carefully read all product packaging and labels prior to use
Lariam (Mefloquine) Tablets: If you are concerned about any unwanted effects please seek medical advice as soon as possible.
Most common unwanted effects: feeling or actually being sick, dizziness, vertigo, loss of balance, headache, sleepiness, sleep problems, diarrhoea, stomach ache. If you feel dizzy, do not drive or carry out tasks requiring a high degree of co-ordination.
Less common unwanted effects: Effects on nervous system: psychiatric reactions which may be disabling and last for more than several weeks. These include unusual changes in mood or behaviour, feelings of worry or anxiety, depression, feelings of persecution, crying, aggression, restlessness, forgetfulness, agitation, confusion, panic and hallucinations. If you experience any of these effects you should immediately stop taking Lariam and consult a doctor.
Other effects: feeling of weakness, breathlessness, muscle cramps, joint pains, muscle pains, tiredness, fever or chills, sweating, loss of appetite, indigestion, a change in the level of certain factors (e.g. white blood cells, platelets, enzymes) in your blood. There have also been rare reports of allergic reactions.
Lariam (Mefloquine) Tablets contain the active ingredient mefloquine.
- Each tablet contains 250mg of mefloquine (as mefloquine hydrochloride).
- The tablets also contain poloxamer, microcrystalline cellulose, lactose, maize starch, crospovidone, ammonium calcium alginate, talc, magnesium stearate.