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Suprecur Nasal Spray contains buserelin (as buserelin acetate, 150 micrograms in each spray). Other ingredients include citric acid, sodium chloride, sodium citrate, benzalkonium chloride and water. It is a nasal spray; one bottle contains 84 spray doses. A pack of Suprecur Nasal Spray contains two individual cardboard boxes wrapped in a clear plastic outer. Each box contains 1 bottle of solution and a spray pump.
Suprecur Nasal Spray is used to treat endometriosis and also as part of a treatment for infertility.
Tell your doctor:
If you are being treated for endometriosis, tell your doctor if you are using oral contraceptives (the pill). You should change to another (barrier) form of contraceptive during treatment with Suprecur Nasal Spray.
Alongside treatment with Suprecur Nasal Spray, you may be given other hormones called gonadotrophins. This combination may cause an increased risk of Ovarian Hyperstimulation Syndrome (OHSS), compared with the use of gonadotrophins alone. The symptoms of OHSS are listed under 'What undesirable effects may Suprecur Nasal Spray cause?'
If you feel dizzy or drowsy after taking this medicine, do not drive or operate machinery.
This medicine is intended for the use in women, however, there is another dosage which may be used in men. Men should not use either dosage if they have had their testes removed.
Follow your doctor's advice about when and how to use your medicine and read the label and leaflet. Your pharmacist may also help if you are not sure. You should start treatment on the first or second day of your period.
The usual dose for the treatment of endometriosis is two sprays (one into each nostril) three times a day. This is best taken in the morning, at mid-day and in the evening. The usual duration of treatment of endometriosis is six months.
For use as part of infertility treatment the usual dose is one spray (in one nostril only) four times a day for about two to three weeks. Some clinics use higher doses. As part of this treatment, you may also be given gonadotrophins, hCG or progesterone if appropriate.
It is very important to use Suprecur Nasal Spray at regular intervals throughout the waking hours.
You can continue to use Suprecur Nasal Spray if you have a cold. Blow your nose well before using the spray. If you are using a nasal decongestant do not use the decongestant for at least 30minutes after you have used Suprecur Nasal Spray.
If you miss a dose of Suprecur Nasal Spray, take another as soon as you remember unless it is nearly time for your next dose. Never double-up on the next dose to make up for the one you missed.
If you take too much Suprecur Nasal Spray tell your doctor as soon as possible.
Suprecur Nasal Spray is not suitable for children or those who have already been through the menopause or 'change of life'.
Any medicine can have side-effects.
You will probably have a period during the first few weeks of treatment. After this your periods will probably stop, although some people may bleed again.
You may notice symptoms such as hot flushes, sweating or you may have a dry vagina, decreased interest in sex or find intercourse painful.
Cysts (swellings) can sometimes occur in the ovaries during treatment with buserelin but do not interfere with treatment.
You may develop Ovarian Hyperstimulation Syndrome (OHSS). The symptoms of this are back pain, sickness, diarrhoea, difficulty in breathing, reduced urine excretion, pain and/or swelling in the lower abdomen and changes in blood, increasing the likelihood of blood clots.
During long term treatment the amount of calcium in bone may decrease. Most of the calcium is regained when treatment is stopped.
Some people find that the nasal spray irritates the nose and may even cause nosebleeds, make you feel hoarse or disturb your sense of taste and smell. If you have any problems tell your doctor. Long term use of this product could lead to development of pituitary adenoma (a tumour of part of the brain). This does not commonly cause problems but if you have persistent headaches or changes in your vision then consult your doctor.
Other side effects which may also occur include:
If you suffer from any of these symptoms, feel unwell after using the spray, or notice anything unusual or unexpected, tell your doctor.
Store your nasal spray between 2C and 25C. Do not freeze it. Do not use it past the expiry date on the bottle.
One bottle has enough solution to last two weeks if you are being treated for endometriosis at the usual dose. You should stop using a bottle at the end of two weeks and start a new bottle. If you are using Suprecur Nasal Spray as part of an infertility treatment the one bottle can be used for up to five weeks after first opening.
KEEP OUT OF THE REACH AND SIGHT OF CHILDREN.
Your medicine could harm them.
If your doctor decides to stop the treatment, return any leftover spray to your pharmacist so that it can be disposed of safely. Only keep it if your doctor tells you to.
Remember this medicine is for you. Only a doctor can prescribe it for you. Never give it to other people. It may harm them, even if they have the same symptoms as you.
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