You should take your Calcitriol capsules swallowed whole with a glass of water, with or without food, once or twice daily depending on what you are being treated for. Your dose may be increased and your blood calcium levels will be monitored. You should continue to take your Calcitriol capsules for as long as recommended by your doctor, which may be several months or years. Do not take any food or Vitamin supplements containing Vitamin D while you are taking Calcitriol capsules.