Risks of applying to much CADESORB to the wound: It is unlikely that too much CADESORB could be applied to the wound. The pKa of CADESORB acid (4.75) dictates that local pH will not drop lower than 1 pH unit either side of this value. It is recommended however that sufficient be applied to cover the wound area (1 ? 2mm) and not leave a large excess surrounding the wound.