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Advocate Large Cat 4-8kg (3)

3 Pipettes
In Stock
Delivery information Product #0016433

Please note images are for illustration purposes and may differ from the product(s) you receive

Advocate is for the treatment & prevention of flea infestation, earmite infestation, roundworm, hookworm and heartworm. It protects your pets against internal & external parasites for four weeks with just one very convenient treatment.

Advocate Large Cat 4-8kg is for cats suffering from, or at risk from, mixed parasitic infections. For the treatment and prevention of flea infestation (Ctenocephalides felis), treatment of ear mite infestation (Otodectes cynotis), prevention of heartworm disease (L3 and L4 larvae of Dirofilaria immitis) and treatment of infections with gastrointesinal nematadoes (l4 larvae, immature adults and adults of Toxocara cati and Ancylostoma tubaeforme). The product can be used as part of a treatment strategy for flea allergy dermatitis (FAD).


Weight of Cat (kg)

Pipette size to be used

Volume (ml)

Imidacloprid (mg/kg bw)

Moxidectin (mg/kg bw)

< 4 kg

Advocate for small cats


Minimum of 10

Minimum of 1

> 4 - < 8kg

Advocate for large cats


10 – 20

1 - 10

> 8kg

Appropriate combination of pipettes

What can Advocate be used for?

Flea treatment and prevention

One treatment prevents further flea infestation for 4 weeks, Pre-existing pupae in the environment may continue to emerge for 6 weeks or longer after treatment is initiated depending uponclimatic conditions. Therefore, it may be necessary to combine Advocate treatment with treatments aimed at breaking the flea life cycle in the surroundings. This can result in more rapid reductions in the household flea population. The product should be administered at monthly intervals when used as part of a treatment strategy for flea allergy dermatitis.

Treatment of ear mite infestation (Otodectes cynotis)

A single dose of the product should be administered. further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment. Do not apply directly to the ear canal.

Heartworm prevention

For prevention of heartworm disease, the product must be applied at regular monthly intervals during the times of year when mosquitoes are present.

Roundworm and hookworm treatment

In areas endemic for heartworm, monthly treatment may significantly reduce the risk of re-infection caused by the respective roundworms and hookworms. In areas non-endemic for heartworm, the product can be used as part of a seasonal prevention programme against fleas and gastrointestinal nematodes.

Extra Information

Advocate spot-on solution for cats is a clear yellow to brownish solution containing 10 % imidacloprid and 1.0 % moxidectin with benzyl alcohol and Butylhydroxytoluene 1 mg/ml (E 321). Each tube of the small cat and ferret presentations contains 0.4 ml (40 mg imidacloprid, 4 mg moxidectin), the large cat presentation contains 0.8 ml (80 mg imidacloprid, 8 mg moxidectin). Blister pack containing 3 or 6 unit dose pipettes: 0.8 ml per pipette.

Dosage for Advocate Large Cat 4-8kg:

The recommended minimum doses for cats are 10 mg/kg bodyweight imidacloprid and 1.0 mg/kg bodyweight moxidectin, equivalent to 0.1ml/kg bodyweight Advocate for cats.

Caution before using Advocate Large Cat 4-8kg:

  • Do not store above 30°C
  • Cats - Do not use in kittens under 9 weeks of age.
  • For cats, ‘Advocate Spot-on Solution for cats’, which contains 10 % imidacloprid and 1.0 % moxidectin, must be used.
  • Do not use in the case of hypersensitivity to the active substances or to any of the excipients.
  • There is limited experience on the use of the product in sick and debilitated animals, thus the product should only be used based on a risk-benefit assessment for these animals.
  • It is recommended that cats and ferrets living in, or travelling to areas endemic for heartworm are treated monthly with the product to protect them from heartworm disease. Whilst the accuracy of diagnosis of heartworm infection is limited, it is recommended that attempts be made to check the heartworm status of any cat and ferret aged over 6 months, before beginning prophylactic treatment, as use of the product on cats or ferrets which have adult heartworms may cause serious adverse effects, including death. If adult heartworm infection is diagnosed, the infection should be treated in accordance with current scientific knowledge.
  • Use of the product may result in transient pruritus in the animal. On rare occasions greasy fur, erythema and vomiting can occur. These signs disappear without further treatment. The product may, in rare cases cause local hypersensitivity reactions. If the animal licks the application site after treatment, transient neurological signs may be observed infrequently. The product may in very rare cases cause at the application site a sensation resulting in transient behavioural changes such as lethargy, agitation, and inappetence.
  • The product tastes bitter. Salivation may occasionally occur if the animal licks the application site immediately after treatment. This is not a sign of intoxication and disappears within some minutes without treatment. Correct application will minimise licking of the application site.
  • Care should be taken that the contents of the pipette or the applied dose does not come into contact with the eyes or mouth of the recipient and/or other animals. Do not allow recently treated animals to groom each other. When the product is applied in 3 to 4 separate spots in larger dogs, specific care should be taken to prevent the animal licking the application sites.
  • Although the product may be safely administered to dogs infected with adult heartworms, it has no therapeutic effect against adult Dirofilaria immitis. It is therefore recommended that all dogs 6 months of age or more, living in areas endemic for heartworm, should be tested for existing adult heartworm infection before being treated with the product.
  • The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Laboratory studies with either imidacloprid or moxidectin in rats and rabbits have not produced any evidence of teratogenic, foetotoxic or maternotoxic effects. Use only according to the risk-benefit assessment.
  • During treatment with Advocate no other antiparasitic macrocyclic lactone should be administered.
  • No interactions between Advocate and routinely used veterinary medicinal products or medical or surgical procedures have been observed.

User Safety

  • Avoid contact with skin, eyes or mouth.
  • Do not eat, drink or smoke during application.
  • Wash hands thoroughly after use.
  • After application do not stroke or groom animals until the application site is dry.
  • In case of accidental spillage onto skin, wash off immediately with soap and water.
  • People with a known hypersensitivity to either benzyl alcohol, imidacloprid or moxidectin should administer the product with caution. In very rare cases the product may cause skin sensitisation or transient skin reactions (for example allergy, irritation or tingling).
  • If the product accidentally gets into eyes, they should be thoroughly flushed with water.
  • If skin or eye symptoms persist, or the product is accidentally swallowed, seek medical attention and show the package insert to the physician.

Environmental Safety

  • Any unused product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
  • Advocate should not be allowed to enter surface waters as it has harmful effects on aquatic organisms: moxidectin is highly toxic to aquatic organisms. Dogs should not be allowed to swim in surface waters for 4 days after treatment.

Advocate Large Cat 4-8kg contains:

  • Imidacloprid, 1-(6-Chloro-3-pyridylmethyl)-N-nitro-imidazolidin-2-ylideneamine is an ectoparasiticide belonging to the chloronicotinyl group of compounds. Chemically, it is more accurately described as a chloronicotinyl nitroguanidine. Imidacloprid is effective against larval flea stages and adult fleas.
  • Moxidectin, 23-(O-methyloxime)-F28249 alpha is a second-generation macrocyclic lactone of the milbemycin family. It is a parasiticide which is active against many internal and external parasites. Moxidectin is active against larval stages (L3, L4) of Dirofilaria immitis. It is also active against gastrointestinal nematodes.
Advocate Large Cat 4-8kg (3)
5 stars

1 out of 1 people found this useful. Yes No Report abuse
Advocate Large Cat 4-8kg (3)
4.7 stars

after using frontline for years with success this year we got a flea infestation. I took one of the cats to the vet to get an injection to relieve his discomfort from itching, and got advocate from the vet, she said she had lost count of the number of customers who have had frontline failure this year, it seems to have lost its efectiveness, the advocate was what she recommended. So far the cats are flea free, and I am ordering more. Fleas on your cat can lead to tape worm and dehydration and depression- it can be very serious, keep your eye on your little four legged friends and give them the love and attention they deserve. I definately recommend this product. Remember to treat your home and car too.

5 out of 5 people found this useful. Yes No Report abuse
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