Aspirin Dispersible Tablets 75mgmay be used to help prevent heart attacks and stroke in patients who have previously suffered such events, in patients who have unstable angina and following by-pass surgery. Please note that Aspirin Dispersible Tablets 75mg are not suitable for general pain relief such as headaches.
How to take Aspirin Dispersible Tablets 75mg: Adults: The usual dose for long-term use is 1-2 tablets (75-150mg) once daily. In some circumstances a higher dose may be appropriate, especially in the short-term, and up to 4 tablets (300mg) a day may be used on the advice of a doctor. Children: Not recommended. These tablets should be dissolved or mixed with water before taking with or after food. Swallow the tablets immediately after dispersing them in water. If symptoms persist you should consult your doctor. If you forget to take a dose, take another as soon as you remember and then your next dose at the usual time. Never take two doses at the same time. If you take more tablets than recommended above, contact your nearest hospital casualty department, or tell your doctor, immediately. Take any remaining tablets and the container with you.
There is a possible association between aspirin and Reye's syndrome when given to children. Reye's syndrome is a very rare disease, which affects the brain and liver, and can be fatal. For this reason aspirin should not be given to children aged under 16 years unless specifically indicated (e.g. for Kawasaki's disease). Salicylates may enhance the effect of oral hypoglycaemic agents, phenytoin and sodium valproate. They inhibit the uricosuric effect of probenecid and may increase the toxicity of sulphonamides.
Aspirin may potentiate the effect of heparin and increases the risk of bleeding with oral anticoagulants, antiplatelet agents and fibrinolytics. Plasma salicylate concentrations may be reduced by concurrent use of corticosteroids, and salicylate toxicity may occur following withdrawal of the corticosteroids. The risk of gastrointestinal ulceration and bleeding may be increased when aspirin and corticosteroids are co-administered. Concurrent use of aspirin and other NSAIDs should be avoided. Use of two or more NSAID preparations increases the risk of serious gastrointestinal haemorrhage. Concurrent administration of carbonic anhydrase inhibitors such as acetazolamide and salicylates may result in severe acidosis and increased central nervous system toxicity. In large doses, salicylates may also decrease insulin requirements. Patients using enteric coated aspirin should be advised against ingesting antacids simultaneously to avoid premature drug release.
Before commencing long-term aspirin therapy for the management of cerebrovascular or cardiovascular disease patients should consult their doctor who can advise on the relative benefits versus the risks for the individual patient.
Aspirin decreases platelet adhesiveness and increases bleeding time. Haematological and haemorrhagic effects can occur, and may be severe. Patients should report any unusual bleeding symptoms to their physician.
Salicylates should be used with caution in patients with a history of peptic ulceration or coagulation abnormalities. They may also induce gastro-intestinal haemorrhage, occasionally major.
They may also precipitate bronchospasm or induce attacks of asthma in susceptible subjects.
Aspirin should be used with caution in patients with impaired renal function (avoid if severe), or in patients who are dehydrated.
Patients with hypertension should be carefully monitored. You should carefully read all product packaging and labels prior to use
Possible side affects from taking Aspirin Dispersible Tablets 75mg: Like many medicines, Dispersible Aspirin may occasionally cause side-effects in some patients, particularly when you first start taking it. Effects may include:
Allergic Reactions- runny nose, itchy skin, swelling and worsening of asthma. Effects on the gastrointestinal system– stomach ulcers or bleeding which can be severe (you may develop bloody or black tarry stools, severe stomach pain and vomit blood), Stomach irritation (mild stomach pain, heartburn and feeling sick) and inflammation of the liver. Effects on the blood- anaemia, changes in numbers and types of blood cells. If you have an increase in number of nose bleeds or notice that you bruise more easily or have more infections talk to your doctor. Effects on the ear- ringing or buzzing in the ear. Salicylism- if you take large doses for a long time you may develop symptoms of salicylism, these include: dizziness, ringing or buzzing in the ear, deafness, sweating, feeling or being sick, headache and confusion. - If you are concerned about any side-effects or have any other unusual effects, tell your doctor immediately and seek advice.
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