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Home PrescriptionAcetylcysteine Amp 200mg 10ml
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Acetylcysteine Amp 200mg 10ml

  • Acetylcysteine Amp 200mg 10ml
  • Acetylcysteine Amp 200mg 10ml is a solution for infusion for intravenous use and is used for the treatment of paracetamol overdose.It is a private prescription item. To purchase this item you must have a private prescription from your doctor or medical profession.
  • To purchase this item you must have a valid prescription.
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Description

Product Code: 0011376

ACETYLCYSTEINE AMP 200MG 10ML is a private prescription item. To purchase this item you must have a private prescription from your doctor or medical profession. If you require any help or assistance with purchasing ACETYLCYSTEINE AMP 200MG 10ML please contact our pharmacy team.
 

What is Acetylcysteine?


It is called Parvolex Solution for Infusion and it is a solution for infusion for intravenous use and each ampoule contains 2 grams of acetylcysteine Ph. Eur. (20% w/v) in 10ml of solution.

Parvolex is a derivative of a naturally occurring amino acid which can protect the liver from damage following paracetamol overdosage.

Parvolex is supplied in clear glass 10ml snap ring ampoules packed in cartons of 10 x 10ml.
 

What is this medicine used for?


Parvolex is used for the treatment of paracetamol overdose.

 

Before you take this medicine


You must tell your pharmacist or doctor if the answer to any of the following questions is “yes”. It may be necessary to change your treatment or give you special advice.

  • Have you ever had asthma or breathing difficulties?
  • Are you allergic to any of the ingredients listed in “What is your medicine”?
  • Are you taking any drugs for epilepsy (e.g. phenytoin, phenobarbitone, primidone or carbamazepine) or the antibiotic, rifampicin?
  • Have you ever suffered from drug abuse or do you drink a lot of alcohol?
  • Are you undernourished, e.g. due to anorexia, or AIDS?
  • Are you pregnant, possibly pregnant or breast-feeding?
 

How do I take Parvolex Solution for Infusion?


Parvolex is given by intravenous infusion into the bloodstream. The infusion fluid used is either 5% dextrose, 0.9% sodium chloride, 0.3% potassium chloride with 5% glucose or 0.3% potassium chloride with 0.9% sodium chloride. For adults, an initial dose of 150mg/kg body weight of Parvolex is given in 200ml infusion fluid over 15 minutes, followed by 50mg/kg in 500ml infusion fluid over the next 4 hours, then 100mg/kg in 1 litre infusion fluid over the next 16 hours. (This gives a total dose of 300mg/kg in 20 hours.)

Children should be treated with the same dose but the quantity of intravenous fluid will be modified to take account of age and weight to avoid fluid overload.

Parvolex is effective in preventing the liver poisoning caused by an overdose of paracetamol if it is taken within 8 hours of the overdose. If it is more than 8 hours, Parvolex becomes less effective as the gap between taking the overdose and starting the Parvolex increases but it can still be of benefit when administered up to 24 hours after the paracetamol overdose. It may also be administered after 24 hours in patients at risk of severe liver damage.

Your doctor may want to perform blood or other tests to monitor your condition.

What if I am given too much Parvolex Solution for Infusion?


If you are given too much Parvolex you may get the ‘allergic’ or ‘hypersensitivity’ side effects listed in the second paragraph of the next section ‘Are there any side effects?’ and they may be more severe.

Tell your doctor if you experience any of these side effects.

Are there any side effects?


As with all medicines, side effects can occur and these may including any of the following:

'Allergic' or 'hypersensitivity' reactions such as nausea, vomiting, irritation at injection site, flushing, itching, rashes, swelling, difficulty breathing, a fall in blood pressure causing dizziness and, more rarely, rapid heart beat or increased blood pressure can occur.

These effects have usually occurred between 15 and 60 minutes after the start of the infusion and, in many cases, are relieved by stopping the infusion. Treatment with other medicines, e.g. antihistamines, may be necessary. Once the reaction is under control, the infusion with Parvolex can be restarted.

In rare instances, the following side effects have occurred:

Coughing, chest tightness or pain, puffy eyes, sweating, feeling unwell, high temperature, warmth, blurred vision, slow heart beat, fainting, facial or eye pain, upset salt balance in the blood, a reduced number of platelets in the blood which makes clotting more difficult, the infusion may leak out of the blood vessel and go into the surrounding tissue, breathing/heart beat stop, noisy breathing in, feeling anxious, joint pain/disease, fits, bluish discoloration from low oxygen levels, decreased levels of potassium or urea in the blood, changes in the heart’s electrical activity, and death.

If you think that this medicine has upset you in ANY way, please tell your doctor.

How to store this medicine


Parvolex Solution for Infusion must be stored below 25°C.

Do not use this medicine after the expiry date shown on the pack.

KEEP THIS AND ALL MEDICINES OUT OF THE REACH AND SIGHT OF CHILDREN

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