1. What is Acebutolol and how does it work?
Acebutolol belongs to a group of medicines called beta-blockers, which block beta receptors in the heart, lungs and other organs of the body. A cebutolol capsules are used in the treatment of high blood pressure and abnormal heart rhythms. When used to treat high blood pressure, it is effective used alone or in combination with other high blood pressure medications, particularly with a thiazide-type diuretic. Beta blockers decrease the force and rate of heart contractions, thus reducing pressure within the circulatory system.
2. What is Acebutolol used for?
- Angina
- Fast, abnormal heart rhythms (tachyarrhythmias)
- High blood pressure (hypertension)
3. How to take Acebutolol
Hypertension
: Initial dosage of 400mg orally once daily at breakfast or 200mg orally twice daily. If response is not adequate within two weeks, dosage may be increased up to 400mg orally twice daily; if the hypertension is still not adequately controlled consideration should be given to adding a second antihypertensive agent such as the calcium antagonist nifedipine or small doses of a thiazide diuretic.
Angina pectoris
: Initial dosage of 400mg orally once daily at breakfast or 200mg twice daily. In severe forms up to 300mg three times daily may be required. Up to 1200mg daily has been used.
Cardiac Arrhythmias
: When given orally, an initial dose of 200mg is recommended. The daily dose requirement for long term anti arrhythmic activity should lie between 400 and 1200mg daily. The dose can be gauged by response, and better control may be achieved by divided doses rather than single doses. It may take up to three hours for maximal anti-arrhythmic effect to become apparent.
Elderly
: There are no specific dosage recommendations for the elderly with normal glomerular filtration rate. Dose reduction is necessary if moderate to severe renal impairment is present (see Section 4.4)
Children
: Paediatric dose has not been established.
For all indications, it is advised that the lowest recommended dosage be used initially.
4. Side Effects
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible.
More common side effects may include
:
Abnormal vision, chest pain, constipation, cough, decreased sexual ability, depression, diarrhea, dizziness, fatigue, frequent urination, gas, headache, indigestion, joint pain, nasal inflammation, nausea, shortness of breath or difficulty breathing, strange dreams, swelling due to fluid retention, trouble sleeping, weakness.
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